国际眼科病理学杂志

Comparison of Topical 0.03% Tacrolimus in Almond and Linseed Oil to Treat Experimentally Induced Keratoconjunctivitis Sicca in Rabbits

Marcos Rogerio Sgrignoli, Leticia Yamasaki, Osimar de Carvalho Sanches, Rogerio Giuffrida, Claudia Lizandra Ricci, Gabriela de Campos Santos, Heloisa Ferreira Duarte do Valle, Luis Felipe da Costa Zulim, Daniele Alves Silva, Karina Maria Basso, Mariele Catherine Alves Silva and Silvia Franco An

Keratoconjunctivitis sicca (KCS), or dry eye syndrome, is a common inflammatory disease of the ocular surface in animals and humans that is characterized by quantitative and/or qualitative tear change. The quantitative alterations are due to an aqueous component deficiency, and the qualitative alterations are due to a lipid or mucin layer deficiency that results in the instability of the pre-corneal tear film.