生殖系统与疾病杂志

New Insides on Vaginal Immunity and Recurrent Infections

Gary Ventolini

 New Insides on VaginalImmunity and Recurrent Infections

Major advances in gene amplification and DNA sequencing technology over the last decade have fundamentally changed our knowledge about the vaginal milieu [1]. Professor Albert Doderlein first reported culturing bacteria from vaginal secretions that were classified in 1928 as Lactobacillus acidophilus, a genus of Gram-positive facultative anaerobic or microaerophilic rod-shaped bacteria. Doderlein found that these bacteria produced lactic acid, which in turn inhibited growth of pathogens both in vitro and in vivo.