药物科学与新兴药物杂志

In Vitro and In Vivo Approaches in DMPK: Tools for Predicting Drug Behavior

Vishwak Patil

Drug metabolism and pharmacokinetics (DMPK) studies are essential in understanding the fate of drugs in the body, including their absorption, distribution, metabolism, and excretion. To predict drug behavior accurately, researchers utilize both in vitro and in vivo approaches. This study explores the tools and methodologies employed in DMPK research, focusing on the complementary roles of in vitro and in vivo studies in predicting drug behavior, optimizing drug development, and ensuring drug safety and efficacy