脊柱与神经外科杂志

Postoperative Ambulatory Status Predicts Survival in Patients with Glioblastoma Multiforme

Leif-Erik Bohman, James H Stephen, Rohan Ramakrishna, James M Schuster and Neil R Malhotra

Postoperative Ambulatory Status Predicts Survival in Patients with Glioblastoma Multiforme

Much attention in the surgical literature has emphasized the survival benefit of maximal resection in patients with Glioblastoma Multiforme (GBM). Preoperative functional status has also been long recognized as a major factor on prognosis, but less attention has been paid to the importance of postoperative neurological function on survival. Our study sought to investigate the survival impact of a particularly severe postoperative motor deficit, the loss of functional ambulation, on survival in patients with newly diagnosed primary GBM.