创伤性应激障碍与治疗杂志

Cognitive Approach on the Influence of the Neuroimmune system on Psychiatric Disorders Followed by Anxiety Disorders

Juan Carter

An inflammatory pathogenesis has been hypothesized for schizophrenia and major misery (MD). In schizophrenia and sadness, contradicting designs oftype-1 vs. type-2 resistant reaction appear to be related with contrasts within the actuation of the enzyme indoleamine 2,3-dioxygenase and within the tryptophan-kynurenine digestion system, coming about in expanded generation of kynurenic corrosive in schizophrenia and diminished generation of kynurenic corrosive in depression. These contrasts are related with an awkwardness within the glutamatergic neurotransmission, which may contribute to an over the top agonist activity of N-methyl-D-aspartate (NMDA) in misery and of NMDA hostility in schizophrenia.