肝脏杂志：疾病与移植

Gastroesophageal Reflux Disease: Current Evaluation and Management

Maxwell M Chait

Gastroesophageal Reflux Disease: Current Evaluation and Management

Gastroesophageal reflux disease (GERD) is the most common upper gastrointestinal disorder in the westernized countries. The worldwide incidence of GERD is increasing as the incidence of H.Pylori is decreasing. There are a variety of esophageal and extraesophageal complications that may be potentially life threatening. Esophageal complications include erosive esophagitis, esophageal stricture, Barrett’s esophagus and adenocarcinoma of the esophagus. Extraesophageal complications include atypical chest pain that can simulate angina pectoris; ear, nose, and throat (ENT) manifestations.