国际心血管研究杂志

Higher Incidence of Acute Aortic Dissections in Winter Months- Results of the German Registry for Acute Aortic Dissection Type A

Mehmet Oezkur, Ernst Weigang, Armin Gorski, Atilla Magyar, Marcus Leistner, Isabell Hoffmann, Maria Blettner and Rainer Leyh

Background: Most cardiovascular events have their peak during the cold winter months. Especially for myocardial infarctions the accumulation is already well described. Several studies have investigated the incidence of acute aortic dissections (AAD) but a seasonal increase of AADs could not be shown yet due to the limited power of these studies. Therefore, we investigated the German Registry for Acute Aortic Dissection Type A (GERAADA) data for seasonal accumulations. Methods: All 2137 patients who have been registered in GERAADA from 7/2006 to 6/2010, which is a prospective, multi-centre registry of the German Society of Thoracic and Cardiovascular Surgery, have been analysed. The incidences per year, quarter, season and month were investigated considering covariates such as age, gender and etiology using poisson regression. Results: The distribution of the incidences differed significantly between the quarters. More patients were treated in quarters IV and I (p=0.002). In the months October-February there were more cases than in the rest of the year (p=0.017). Although age, gender, the underlying disease (p<0.001) as well as arterial hypertension had an impact on the incidence of AADs (p=0.005), the distribution on the quarters was not influenced by these variables (Poisson regression p>0.5). Conclusions: Our data show that there is a peak of surgically treated AADs within German speaking Europe during winter months independent from patient related factors and the aetiology of the AAD.