肝脏杂志:疾病与移植

Primary Hepatic Amyloidosis Associated with Chronic Hepatitis C Infection: A Case Study

Pratim Sengupta* , Tapas Roy , Atreyee Chaudhuri and Kavita Rathore

Primary hepatic amyloidosis is an infrequent condition marked by the accumulation of amyloid protein within the liver. This case study presents a case of a 38-year-old male with chronic hepatitis C infection who presented with abdominal discomfort and hepatomegaly. Liver biopsy revealed amyloid deposits within the liver parenchyma, and Congo red staining confirmed the diagnosis of hepatic amyloidosis. The patient received antiviral treatment for hepatitis C along with additional supportive therapy, leading to an improvement in their liver enzyme levels. This case underscores the significance of including hepatic amyloidosis in the differential diagnosis for individuals with chronic hepatitis C, especially when presenting with hepatomegaly and elevated liver enzymes. The timely recognition and efficient handling are essential to avoid further harm to the liver and improve the outcomes for patients. Additional research is required to deepen our understanding of the connection between hepatitis C infection and hepatic amyloidosis.