国际心血管研究杂志

Study the Effect of Type II Diabetes Alone and Diabetes Associated with Hypertension on Left Atrial Volume as a Sensitive Predictor of Left Atrial Dysfunction: A Case-Control Study

Nancy Ibraheem Mohammed Abdo, Mahmoud Mohammed Abdou Youssof, Ayman Ahmed Abd EL-Aziz and Ahmed Hassan Hosny Eladawy*

Introduction: It has been shown that the volume of the left chamber is a delicate mark of the level of diastolic brokenness. The objective of this study was supposed to evaluate left atrial volume in patients with Type 2 Diabetes Mellitus (T2DM) and level of diastolic brokenness in patients with type 2 DM in presence or nonappearance of crucial hypertension and relationship of this limits with section and clinical revelations.

Results: Twenty-two diabetic patients were taken into account and divided into two groups: Patient gathering: were broken down into two groups: Subgroup I: contained 30 patients with straightforward sort 2 Diabetes Mellitus (DM) without foundational blood vessel hypertension. II Subgroup: involved 30 patients with straightforward kind 2 DM with fundamental blood vessel hypertension. Systolic left ventricular function was normal in all of the study’s participants. Control subjects: comprised 60 subjects who were matched according to age (48 years ± 8 years), had normal clinical examination and Electrocardiogram (ECG), and were all free of cardiovascular symptoms. Just the pulse fundamentally expanded in the diabetes mellitus bunch among the segment information of our patients and control gatherings. Left Atrial Volume (LAV) and Left Atrial Volume record both increased significantly in the diabetic group in comparison to the control group. Despite the fact that LA breadth was not significantly different between the two gatherings. Because these results indicate enlargement of the Left Atrium (LA) in diabetic patients, LAV and LAVI perform better than the conventional M-mode LA dimension in assessing the size of the LA. Diabetic patients had significantly lower E wave peak velocity, A wave peak velocity, E/A ratio, and Tissue Doppler Imaging (TDI) E’ and A’ when compared to the control group.

Conclusion: The biplane area length method is easier to use to calculate left atrial volume than the antero-posterior diameter measurement. Left atrial volume record expanded in asymptomatic sort 2 diabetes mellitus, and especially reflects LV diastolic brokenness in type 2 diabetes mellitus.

Left atrial volume amplification is related with LA brokenness in type 2 diabetes mellitus as assessed by trans-mitral Doppler and tissue Doppler imaging. The presence of hypertension was the most free indicator of the expanded Left Atrial Volume Index (LAVI) in type II DM, with expansion in the gamble.