应用生物信息学与计算生物学杂志

A Linkage Based Imputation Method for Missing SNP Markers in Association Mapping

Yi Xu, Yajun Wu, Michael G Gonda and Jixiang Wu

A Linkage based Imputation Method for Missing SNP Markers in Association Mapping

Association mapping has been widely used in detecting genetic markers associated with traits of importance in research areas such as plant breeding, human disease and animal breeding. In recent years, various useful statistical methods and computing tools have been developed for association mapping studies. One of the critical challenges in association mapping is missing markers.