应用生物信息学与计算生物学杂志

Structural Modeling of Plant Secondary Metabolites Characterized by an Inhibitory Potential of Insect Enzymes

Rabeb Shaiek,Faten Raboudi,Nada Ayadi,Sarra Aloui, Rachid Salghi and Sami Fattouch

Structural Modeling of Plant Secondary Metabolites Characterized by an Inhibitory Potential of Insect Enzymes

Management of pests in the world is facing economic and environmental challenges posed by the majority of chemical pesticides. The identification of new effective insecticides is essential to fight against these parasites. Inhibition of insect enzymes has been opined as a possible mode of action of various plant secondary metabolites. However, it is necessary to gain knowledge about the binding mode of these metabolites to the target region so as to facilitate an understanding of the evolution of novel molecules for pest management.