Christopher Collins
Genetics play a major role in every aspect of our lives; they determine our hair colour, eye colour, height, disease risks, gifts and some of our mannerisms. As such they also play a large function in our response to exercise and physical stressors. The gene AMPD1 is a protein coding gene, encoding adenosine monophosphate deminase 1. AMPD1 catalyses the deamination (the removal of an amine group from a molecule) of AMP to IMP in skeletal muscle, deficiency of the AMPD1 enzyme is a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy. It appears that those with at least one T variant in AMPD1 (rs17602729) require longer rest periods between bouts of weight training, require longer between sessions and have increased perceived pain post training.
English 
Spanish 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi